Session 1:

The Intrarenal Renin Angiotensin System

Moderator:

Gabriel Navar, USA

09:00 – 09:20

Tubular ACE and blood pressure

Romer Gonzalez-Villalobos, USA

09:20 - 09:40

Tubular renin control of blood pressure

Nirupama Ramkumar, USA

09:40 - 09:50

Oral Presentation from Abstract Submission: Activation of the intrarenal renin angiotensin system in polycystic kidney disease

T.Saigusa, USA

09:50 – 10:00

Oral Presentation from Abstract Submission: Fenofibrate therapy alleviates angiotensin II-dependent hypertension CYP1A1-REN-2 Transgenic rats

S. Jichova, Czech Republic

10:00 – 10:40

Coffee Break and Poster Viewing

Session 2:

Intratubular Crosstalk: Proteases and Channel Interaction

Moderator:

Kimio Tomita, Japan

Tom Kleyman, USA

10:40 – 11:00

Regulation of ENaC by extracellular proteases

Christoph Korbmacher, Germany

11:00 - 11:20

Regulation of ENaC by plasmin

Boye Jensen, Denmark

11:20 - 11:40

Kallikrein, ENaC and K+ handling

Nicolas Picard, France

11:40 - 11:50

Oral Presentation from Abstract Submission : Proteolytic activation of the human epithelial sodium channel (ENAC) by the serine protease Trypsin IV and the cysteine protease cathepsin-S

S. Haertels, Germany

11:50 – 12:00

Oral Presentation from Abstract Submission: Regulation of epithelial sodium channel by epidermal growth factors and its complications in hypertension and polycystic kidney diseases

T. Pavlov, USA

12:00 - 14:00

Networking Lunch & Poster Viewing

Session 3:

The Intrarenal Nucleotide/Nucleoside System

Moderators:

Jens Leipziger, Denmark

Volker Vallon, USA

14:00 - 14:30

Keynote Lecture: Nucleotides as Paracrine factors

Paul Insel, USA

14:30 - 14:50

Ectonucleotidases in the kidney

Bellamkonda Kishore, USA

14:50 - 15:10

Purinergic regulation of tubule ion transport

James Stockand, USA

15:10 - 15:20

Oral Presentation from Abstract Submission: Basolateral p2x receptors, luminal furosemide and a novel view on loop-diuretic-induced urinary acidification

P. de Bruijin, Denmark

15:20 - 15:30

Oral Presentation from Abstract Submission: Biosensors as a novel tool to assess atp and h2o2 levels and their acute release in the kidney

O. Palygin, USA

15:30 - 16:10

Coffee Break and Poster Viewing

Session 4:

Intrarenal Nitric Oxide and Endothelin

Moderators:

Donald Kohan, USA

David Pollock, USA

16:10 - 16:30

NO/ET in the collecting duct

Jennifer Pollock, USA

16:30 - 16:50

NO/ET in the thick ascending limb

Jeff Garvin, USA

16:50 - 17:10

Nitric oxide, flow and the macula densa

Ruisheng Liu, USA

17:10 - 17:20

Oral Presentation from Abstract Submission: Role of polycystins, atp and calcium signaling in flow-stimulated collecting duct endothelin-1 production

D. Kohan, USA

17:20 - 17:30

Oral Presentation from Abstract Submission: Impaired pressure natriuresis and urinary et-1 excretion in a rat model of type i diabetes mellitus

G. Culshaw, United Kingdom